This review analyses the interactions between low calorie sweeteners and cells in the gut, and the effect on glucose absorption and insulin. The studies analysed in this paper show that low calorie sweeteners do not have any effects on appetite, subsequent food intake, insulin or blood glucose levels.

This study, undertaken by a team of New Zealand and American researchers, examined the diets of people who had lost weight and are maintaining their slimness, compared to people with a normal weight. The researchers reported that weight-loss maintainers consumed three times the amount of low calorie soft drinks per day than the normal weight people.

This study was conducted to see whether small changes in diet and physical activity could prevent excessive weight gain in overweight children. Families in the study were randomly assigned to either the "America on the Move" group or the self-monitor-only group. Families in the America on the Move group were asked to walk an extra 2000 steps a day and replace dietary sugar with a low calorie sweetener. The study concluded that the small changes could be useful in addressing childhood obesity.

This paper reviews laboratory, clinical and epidemiological studies and concludes that low calorie sweeteners as useful tools in reducing calorie intake.

This review investigates the evidence for the effect of aspartame on weight loss, weight management and energy intakes. The researchers concluded that replacing sugar-sweetened beverages with aspartame sweetened beverages led to significant reductions in calorie intake and weight.

This review analyses the extensive body of science available on low calorie sweeteners. It concludes that the science does not support the concept that the consumption of low calorie sweeteners leads to an increase in calorie intake and body weight.

This review explores the effect that low calorie sweeteners have on hunger and food intake. Both long-term and short-term studies have shown that the consumption of food and drinks sweetened with aspartame is associated either with no change or with a reduction in food intake. The review concludes that low calorie sweeteners have never been found to cause weight gain.